Risk of development of Type 2 diabetes is usually associated with obesity. In this there is excess body fat deposition around abdomen, leading to resistance of insulin. Conversely, diabetes can exacerbate obesity through medication side effects like weight gain and by influencing metabolic processes that promote fat storage. The intricate interplay between diabetes and obesity underscores the importance of holistic approaches to manage both conditions simultaneously.
Metabolism is very crucial for orderly function of body. In obese individuals, adipose tissues secrete cytokines that disrupts this metabolic homeostasis leading to insulin resistance. This in turn exacerbate hyperglycaemia. Addition to these adipose tissues expand triggering changes in adipokine secretion that contributes to metabolic dysfunction and systemic inflammation.
Obesity is an extremely complex condition that can be influenced by many factors such as the choice of lifestyle, some underlying health conditions, and food habits. Sedentary lifestyle along with poor diet can lead to gain in weight contributing to obesity